The problem of multiple NVMe drives in a PC desktop today

If you have a NVME SSD then you would install it in the best or fastest NVME slot This is normally the slots support by your CPU unless

Yes, your notebook has a slot that supports both SATA and NVMe SSD''s NVMe SSD's would provide faster readwrite speeds than SATA Below is

m2 slot pc 2 solution offers considerably faster storage performance and support for both PCIe and SATA interface for SSD devices Intel® GbE LAN with

m2 slot mainboard The Gigabyte motherboard has 3 slots available, marked M2A_CPU, M2B_SB and M2C_SB I guess M2A_CPU has direct lanes to the CPU, the others are